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BRAF [V599E] Recombinant Human Protein

Catalog number: PV3849

 Related applications: Protein Assays and Analysis | Target & Lead Identification & Validation

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Description

BRAF acts upstream of MEK in the MAP kinase pathway and is involved in cell division, differentiation, and secretion. The BRAF mutant V599E is oncogenic and found in a variety of cancers.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Mass: 10 µg
Gene ID: 10488, 673
Species: Human
Target Gene: v-raf murine sarcoma viral oncogene homolog B1
Gene Aliases: BRAF V599E
Kinase Group: Ser⁄Thr Kinases: TKL Group
Product Size: 10 µg
Protein Family: Kinases & Inhibitors
Protein Subtype: Serine⁄Threonine Kinases
Accession Number: NP_004324.1, V599E
Molecular Weight: 67.1 kDa
Research Category: Signal Transduction, Oncology
System Compatibility: LanthaScreen® Substrate, LanthaScreen® Antibody, Z'-LYTE™
Validated Application: Kinase Assay
Protein Length or Portion (a.a.): aa 416-766
Protein Tag or Fusion: GST Tag
Tag Position: N-Terminal
Expression: Baculovirus
Kinase Family: RAF Kinase Family
Protein Form: Catalytic, Recombinant
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 50 mM Tris, pH 7.5, 150 mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

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