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ABL1 [G250E] Recombinant Human Protein

Catalog number: PV3865

 Related applications: Protein Assays and Analysis | Target & Lead Identification & Validation

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Description

The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. The G250E mutant is a Gleevec resistant form of ABL1.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Gene ID: 10488, 25
Species: Human
Target Gene: c-abl oncogene 1, receptor tyrosine kinase
Gene Aliases: ABL1 G250E, ABL, c-ABL
Product Size: 10 µg
Protein Form: Full Length, Cytoplasmic, Recombinant
Protein Family: Kinases & Inhibitors
Protein Subtype: Cytoplasmic Tyrosine Kinases
Accession Number: NP_005148.2, G250E
Molecular Weight: 125.5 kDa
Research Category: Signal Transduction, Oncology
System Compatibility: LanthaScreen® Substrate, LanthaScreen® Antibody, Z'-LYTE™, Omnia® Bulk Substrate
Validated Application: Kinase Assay
Protein Length or Portion (a.a.): Full Length (G250E)
Protein Tag or Fusion: His Tag
Expression: Baculovirus
Kinase Family: ABL Kinase Family
Kinase Group: Tyrosine Kinases
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% NP-40, 2 mM DTT and 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

Documents

Manuals & protocols