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CDK7/Cyclin H/MNAT1 Recombinant Human Protein

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Description

The trimeric complex of CDK7, cyclin H and MNAT1, functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This complex is thought to serve as a direct link between the regulation of transcription and the cell cycle.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Gene ID: 1022, 1385, 1387, 1390, 4331, 902
Species: Human
Target Gene: cyclin-dependent kinase 7
Gene Aliases: CDK7/Cyclin H/MNAT1
Kinase Group: Ser⁄Thr Kinases: CMCG Group
Product Size: 10 µg
Protein Family: Kinases & Inhibitors
Protein Subtype: Serine⁄Threonine Kinases
Accession Number: NP_001790, Q130R I NP_001230 I NP_002422
Molecular Weight: 43.2⁄42.6⁄40.5 kDa
Research Category: Signal Transduction, DNA Replication & Repair, Cell Cycle & Proliferation
System Compatibility: Adapta™
Validated Application: Kinase Assay
Protein Tag or Fusion: His Tag
Expression: Baculovirus
Kinase Family: CDK and CHK Kinase Family
Protein Form: Full Length, Recombinant
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

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