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KIT [T670I] Recombinant Human Protein

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Description

KIT is a proto-oncogene encoding a transmembrane tyrosine kinase receptor for stem cell factor required for normal hematopoiesis, melangenesis and gametogenesis. KIT T670I is a Gleevec resistant form of KIT.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_000213, T670I
Expression: Baculovirus
Gene Aliases: KIT T670I, cKit, PBT
Gene ID: 3815, 9586
Kinase Family: PDGFR Kinase Family
Kinase Group: Tyrosine Kinases
Molecular Weight: 53.3 kDa
Product Size: 10 µg
Protein Family: Kinases & Inhibitors
Protein Form: Cytoplasmic,Recombinant
Protein Length or Portion (a.a.): aa 544-976; T670I
Protein Subtype: Receptor Tyrosine Kinases
Protein Tag or Fusion: His Tag
Research Category: Signal Transduction
Shipping Condition: Dry Ice
Species: Human
System Compatibility: LanthaScreen® Antibody,LanthaScreen® Substrate,Omnia® Bulk Substrate,Z'-LYTE™
Target Gene: v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Validated Application: Kinase Assay

Contents & storage

Storage Buffer: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.