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Thermo Scientific™

EGFR (ErbB1) [L861Q] Recombinant Human Protein

Catalog number: PV3873
Thermo Scientific™

EGFR (ErbB1) [L861Q] Recombinant Human Protein

Catalog number: PV3873
Catalog Number
PV3873
Unit Size
10 µg
Price (USD)
451.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
100 µg
Price (USD)
1,546.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
1 mg
Price (USD)
6,570.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
PV387310 µg
451.00
Your Price:
***
PR7435A100 µg
1,546.00
Your Price:
***
PV41911 mg
6,570.00
Your Price:
***
Product Overview
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FAQ
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Additional Information
Recommendations
The epidermal growth factor receptor is a receptor tyrosine kinase that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. The EGFR L861Q mutation is an Iressa-responsive mutant observed in the clinic.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number
NP_005219.2; L861Q
Assay Entry
Biochemical binding/kinetic, Biochemical terbium phospho-specific activity, Biochemical europium phospho-specific activity
Kinase Group
Tyrosine Kinases
Mass
10 µg
Shipping Condition
Dry Ice
System Compatibility
LanthaScreen™ Antibody, LanthaScreen™ Substrate, Zin-LYTE™, Omnia™ Bulk Substrate
Tag Position
N-Terminal
Target Entry
EGFR L861Q
Target Gene
Epidermal growth factor receptor
Expression System
Baculovirus
Form
Liquid
Protein Family
Kinases & Inhibitors
Protein Form
Recombinant, Cytoplasmic
Protein Subtype
Receptor Tyrosine Kinases
Research Category
Oncology, Signal Transduction
Species
Human
Validated Application
Kinase Assay
Gene ID (Entrez)
114294, 1956
Molecular Weight
90.5 kDa
Purity
65% by SDS-PAGE
Quantity
10 µg
Gene Alias
EGFR (ErbB1) L861Q
KinaseFamily
EGF Receptor (ErbB) Kinase Family
Protein Length
aa 668-1210: L858R, aa 668-1210; L861Q
Recombinant
Yes
Protein Tag
GST Tag

Contents & Storage

Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

Figures

Frequently asked questions (FAQs)

Citations & References