CHEK2 (CHK2) is a serine⁄threonine kinase and a component of the DNA damage checkpoint pathway. A mutation in this gene has been linked to cancer. CHK2 is activated by DNA damage and phosphorylates several modulators of cell cycle control including tumor suppressor proteins.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NP_009125
Molecular Weight
66 kDa
Quantity
1 mg
Gene Alias
CHEK2 (CHK2)
KinaseFamily
RAD53 Kinase Family
Recombinant
Yes
Protein Tag
His Tag
Kinase Group
Ser/Thr Kinases: CAMK Group
Shipping Condition
Dry Ice
Expression System
Baculovirus
Protein Form
Full Length
Form
Frozen
Validated Application
Kinase Assay
Species
Human
Research Category
Drug Development
Contents & Storage
Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.04% Triton X-100, 4mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.