CHEK2 (CHK2) is a serine⁄threonine kinase and a component of the DNA damage checkpoint pathway. A mutation in this gene has been linked to cancer. CHK2 is activated by DNA damage and phosphorylates several modulators of cell cycle control including tumor suppressor proteins.
For Research Use Only. Not for use in diagnostic procedures.
RAD53 Kinase Family
Ser/Thr Kinases: CAMK Group
Contents & Storage
Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.04% Triton X-100, 4mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.