PBK (TOPK) is a serine⁄threonine kinase that is related to the dual specific mitogen-activated protein kinase kinase (MAPKK). The kinase is up-regulated in a variety of hematological malignancies, participates in activating lymphoid cells, and supports testicular function (spermatogenesis).
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NP_060962
Gene ID (Entrez)
114294, 55872
Molecular Weight
41 kDa
Purity
90% by SDS-PAGE
Quantity
10 µg
Gene Alias
PBK (TOPK)
KinaseFamily
TOPK Kinase Family
Host Species
Insect
Recombinant
Yes
Protein Tag
His Tag
Kinase Group
Ser⁄Thr Kinases: Other
Shipping Condition
Dry Ice
Target Gene
PDZ binding kinase
Expression System
Baculovirus
Protein Family
Kinases & Inhibitors
Protein Form
Recombinant, Full Length
Form
Liquid
Protein Subtype
Serine/Threonine Kinases
Validated Application
Kinase Assay
Species
Human
Research Category
Drug Discovery: Signal Transduction
Contents & Storage
Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% Glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.