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Thermo Scientific™

KIT [V654A] Recombinant Human Protein

Catalog number: PV4132
Thermo Scientific™

KIT [V654A] Recombinant Human Protein

Catalog number: PV4132
Catalog Number
PV4132
Unit Size
10 µg
Price (USD)
451.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
100 µg
Price (USD)
1,546.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
1 mg
Price (USD)
6,570.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
PV413210 µg
451.00
Your Price:
***
PR7738A100 µg
1,546.00
Your Price:
***
PV42911 mg
6,570.00
Your Price:
***
Product Overview
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Additional Information
Recommendations
KIT is a proto-oncogene encoding a transmembrane tyrosine kinase receptor for stem cell factor required for normal hematopoiesis, melangenesis and gametogenesis. Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism. The clinically observed V654A mutant has been demonstrated to be resistant to inhibition with imatinib.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number
NP_000213, V654A
Assay Entry
Biochemical binding/kinetic, Biochemical terbium phospho-specific activity, Biochemical europium phospho-specific activity
Kinase Group
Tyrosine Kinases
Mass
10 µg
Shipping Condition
Dry Ice
System Compatibility
LanthaScreen™ Antibody, LanthaScreen™ Substrate
Tag Position
N-Terminal
Target Entry
KIT V654A
Target Gene
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Expression System
Baculovirus
Form
Liquid
Protein Family
Kinases & Inhibitors
Protein Form
Recombinant, Cytoplasmic
Protein Subtype
Receptor Tyrosine Kinases
Research Category
Signal Transduction
Species
Human
Validated Application
Kinase Assay
Format
Kit
Gene ID (Entrez)
3815, 4775
Molecular Weight
53.2 kDa
Purity
50% by SDS-PAGE
Quantity
10 µg
Gene Alias
KIT V654A
KinaseFamily
PDGFR Kinase Family
Protein Length
aa 544-976; V654A
Recombinant
Yes
Protein Tag
His Tag

Contents & Storage

Storage Buffer: 50 mM Tris (pH 7.5), 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% Glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

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Frequently asked questions (FAQs)

Citations & References