BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It is activated by somatic point mutation in human cancer, and is thought to play a role in the postsynaptic responses of hippocampal neuron.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NP_004324.2
Molecular Weight
113.6 kDa
Quantity
1 mg
Gene Alias
BRAF, BRAF1
KinaseFamily
RAF Kinase Family
Recombinant
Yes
Protein Tag
GST Tag
Kinase Group
Ser⁄Thr Kinases: TKL Group
Shipping Condition
Dry Ice
Expression System
Baculovirus
Protein Form
Full Length
Form
Frozen
Validated Application
Kinase Assay
Species
Human
Research Category
Drug Development
Contents & Storage
Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.