BRAF acts upstream of MEK in the MAP kinase pathway and is involved in cell division, differentiation, and secretion. The BRAF mutant V599E is oncogenic and found in a variety of cancers.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NP_004324.1, V599E
Molecular Weight
67.1 kDa
Quantity
1 mg
Gene Alias
BRAF V599E
KinaseFamily
RAF Kinase Family
Recombinant
Yes
Protein Tag
GST Tag
Kinase Group
Ser⁄Thr Kinases: TKL Group
Shipping Condition
Dry Ice
Expression System
Baculovirus
Protein Form
Catalytic
Form
Frozen
Validated Application
Kinase Assay
Species
Human
Research Category
Drug Development
Contents & Storage
Storage Buffer: 50 mM Tris, pH 7.5, 150 mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.