The trimeric complex of CDK7, cyclin H and MNAT1, functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This complex is thought to serve as a direct link between the regulation of transcription and the cell cycle.
For Research Use Only. Not for use in diagnostic procedures.
NP_001790, Q130R I NP_001230 I NP_002422
70% by SDS-PAGE
CDK and CHK Kinase Family
Ser⁄Thr Kinases: CMCG Group
Kinases & Inhibitors
Recombinant, Full Length
Drug Discovery: Cell Cycle & Proliferation, Signal Transduction
Contents & Storage
Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.