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Thermo Scientific™

CDK7/Cyclin H/MNAT1 Recombinant Human Protein

Catalog number:  PV4186

Related applications:

Protein Assays and Analysis

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Description

The trimeric complex of CDK7, cyclin H and MNAT1, functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This complex is thought to serve as a direct link between the regulation of transcription and the cell cycle.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_001790, Q130R I NP_001230 I NP_002422
Kinase Group: Ser⁄Thr Kinases: CMCG Group
Shipping Condition: Dry Ice
Expression System: Baculovirus
Form: Frozen
Protein Form: Full Length
Research Category: Drug Development
Species: Human
Validated Application: Kinase Assay
Molecular Weight: 126.3 kDa
Gene Alias: CDK7/Cyclin H/MNAT1
KinaseFamily: CDK and CHK Kinase Family
Protein Tag: His Tag

Contents & storage

Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.