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Thermo Scientific™
MAP3K10 (MLK2) Recombinant Human Protein
Catalog number: PV4195
Thermo Scientific™
MAP3K10 (MLK2) Recombinant Human Protein
Catalog number: PV4195
Product Overview
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Additional Information
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MAP3K10 (MLK2) is a serine⁄threonine kinase which has been shown to activate MAPK8⁄JNK and MKK4⁄SEK1. This kinase itself can be phoshorylated, and is thus activated by JNK kinases. MAP3K10 functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NP_002437
Molecular Weight
131.2 kDa
Quantity
1 mg
Gene Alias
MAP3K10 (MLK2)
KinaseFamily
MLK Kinase Family
Host Species
Insect
Recombinant
Yes
Protein Tag
GST Tag
Kinase Group
Ser⁄Thr Kinases: TKL Group
Shipping Condition
Dry Ice
Expression System
Baculovirus
Protein Family
Kinases & Inhibitors
Protein Form
Recombinant, Full Length
Form
Liquid
Protein Subtype
Serine/Threonine Kinases
Validated Application
Kinase Assay
Species
Human
Research Category
Drug Discovery: Signal Transduction
Contents & Storage
Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.