The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells. TEK signaling appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis, and defects in TEK are associated with inherited venous malformations.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NP_000450
Molecular Weight
61.5 kDa
Quantity
1 mg
Gene Alias
TEK (Tie2)
KinaseFamily
TIE Kinase Family
Recombinant
Yes
Protein Tag
GST Tag
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
Expression System
Baculovirus
Protein Form
Cytoplasmic
Form
Frozen
Validated Application
Kinase Assay
Species
Human
Research Category
Drug Development
Contents & Storage
Storage Buffer: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.