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PDGFRA [D842V] Recombinant Human Protein

Catalog number:  PV4203

Related applications:

Pharma & Biopharma

| Protein Assays and Analysis

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Description

PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. PDGFRA D842V is expressed in a high percentage of epithelial ovarian cancers and is implicated in the pathogenesis of acute myelogenous leukemia.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_006197, D842V
Assay Entry: Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical europium phospho-specific activity, Biochemical binding/kinetic
Kinase Group: Tyrosine Kinases
Shipping Condition: Dry Ice
System Compatibility: LanthaScreen® Antibody, LanthaScreen® Substrate, Zin-LYTE™, Omnia® Bulk Substrate
Target Entry: PDGFRA D842V
Target Gene: platelet-derived growth factor receptor, alpha polypeptide
Expression System: Baculovirus
Protein Family: Kinases & Inhibitors
Protein Form: Recombinant, Cytoplasmic
Protein Subtype: Receptor Tyrosine Kinases
Research Category: Oncology, Signal Transduction
Species: Human
Validated Application: Kinase Assay
Gene ID (Entrez): 114294, 5156
Molecular Weight: 89.7 kDa
Gene Alias: PDGFRA D842V, PDGFR alpha
KinaseFamily: PDGFR Kinase Family
Protein Length: aa 550-1089; D842V
Protein Tag: GST Tag

Contents & storage

Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% Glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.