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Thermo Scientific™

JAK2 [V617F] Recombinant Human Protein, JH1 and JH2 Domains

Catalog number:  PV4347

Related applications:

Protein Assays and Analysis

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Description

JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. This kinase contains both the JH1 (catalytic) and JH2 (pseudokinase) domains of JAK2. The V617F mutation has been shown to be a cause of polycythemia vera.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_004963
Kinase Group: Tyrosine Kinases
Shipping Condition: Dry Ice
Expression System: Baculovirus
Form: Frozen
Protein Form: Catalytic
Research Category: Drug Development, Signal Transduction
Species: Human
Validated Application: Kinase Assay
Gene ID (Entrez): 3717
Molecular Weight: 97.9 kDa
Gene Alias: JAK2 JH1 JH2 V617F
KinaseFamily: JAK Kinase Family
Protein Tag: GST Tag

Contents & storage

Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.