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Thermo Scientific™

FGFR3 [K650E] Recombinant Human Protein

Catalog number: PV4392
Thermo Scientific™

FGFR3 [K650E] Recombinant Human Protein

Catalog number: PV4392
Catalog Number
PV4392
Unit Size
10 µg
Price (USD)
452.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
1 mg
Price (USD)
6,610.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
100 µg
Price (USD)
1,556.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
PV439210 µg
452.00
Your Price:
***
PV44281 mg
6,610.00
Your Price:
***
PR8155A100 µg
1,556.00
Your Price:
***
Product Overview
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FAQ
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Additional Information
Recommendations
FGFR3 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy. The K650E mutation leads to constitutive activation and the neonatal lethal disorder TDII.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number
NP_000133; K650E
Assay Entry
Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Kinase Group
Tyrosine Kinases
Mass
10 µg
Shipping Condition
Dry Ice
System Compatibility
LanthaScreen™ Antibody, LanthaScreen™ Substrate, Zin-LYTE™, Omnia™ Bulk Substrate
Tag Position
N-Terminal
Target Entry
FGFR3 K650E
Target Gene
fibroblast growth factor receptor 3
Expression System
Baculovirus
Form
Liquid
Protein Family
Kinases & Inhibitors
Protein Form
Recombinant, Cytoplasmic
Protein Subtype
Receptor Tyrosine Kinases
Research Category
Oncology, Signal Transduction
Species
Human
Validated Application
Kinase Assay
Molecular Weight
49.8 kDa
Purity
75% by SDS-PAGE
Quantity
10 µg
Gene Alias
FGFR3 K650E
KinaseFamily
FGF Receptor Kinase Family
Protein Length
aa 398-806; K650E
Recombinant
Yes
Protein Tag
His Tag

Contents & Storage

Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

Figures

Frequently asked questions (FAQs)

Citations & References