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FGFR3 [K650E] Recombinant Human Protein

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FGFR3 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy. The K650E mutation leads to constitutive activation and the neonatal lethal disorder TDII.
For Research Use Only. Not for use in diagnostic procedures.


Form: Frozen
Species: Human
Gene Aliases: FGFR3 K650E
Kinase Group: Tyrosine Kinases
Product Size: 1 mg
Accession Number: NP_000133; K650E
Molecular Weight: 49.8 kDa
Research Category: Drug Development
Protein Tag or Fusion: His Tag
Validated Application: Kinase Assay
Expression: Baculovirus
Kinase Family: FGF Receptor Kinase Family
Protein Form: Cytoplasmic
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.


Manuals & protocols