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Thermo Scientific™

FGFR3 [K650E] Recombinant Human Protein

Catalog number:  PV4428

Related applications:

Protein Assays and Analysis

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Description

FGFR3 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy. The K650E mutation leads to constitutive activation and the neonatal lethal disorder TDII.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_000133; K650E
Kinase Group: Tyrosine Kinases
Shipping Condition: Dry Ice
Expression System: Baculovirus
Form: Frozen
Protein Form: Cytoplasmic
Research Category: Drug Development
Species: Human
Validated Application: Kinase Assay
Molecular Weight: 49.8 kDa
Gene Alias: FGFR3 K650E
KinaseFamily: FGF Receptor Kinase Family
Protein Tag: His Tag

Contents & storage

Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.