The receptor tyrosine kinase RET is a member of the cadherin superfamily. RET plays a crucial role in neural crest development, and can undergo oncogenic activation by cytogenetic rearrangement. The Y791F mutant has been observed clinical in association with cancer.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NP_055124, Y791F
Molecular Weight
79 kDa
Quantity
1 mg
Gene Alias
RET Y791F
KinaseFamily
RET Kinase Family
Recombinant
Yes
Protein Tag
GST Tag
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
Expression System
Baculovirus
Protein Form
Cytoplasmic
Form
Frozen
Validated Application
Kinase Assay
Species
Human
Research Category
Drug Development
Contents & Storage
Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.