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CDK5/p25 Recombinant Human Protein

Catalog number: PV4676

 Related applications: Protein Assays and Analysis | Target & Lead Identification & Validation

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Description

CDK5 plays a critical role in neuron development. The disregulation of the CDK5 and the truncated activator p25 is believed to be involved in neurodegenerative diseases such as Alzheimer's, Parkinson's, and Amyotrophic Lateral Sclerosis. This protein is coexpressed and copurified with p25.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Species: Human
Target Gene: cyclin-dependent kinase 5
Gene Aliases: CDK5/p25, CDK5R
Kinase Group: Ser⁄Thr Kinases: CMCG Group
Product Size: 10 µg
Protein Family: Kinases & Inhibitors
Protein Subtype: Serine⁄Threonine Kinases
Accession Number: NP_004926.1 I NP_003876
Molecular Weight: 36.7⁄51.0 kDa
Research Category: Signal Transduction, Cell Cycle & Proliferation
System Compatibility: Z'-LYTE™
Validated Application: Kinase Assay
Protein Tag or Fusion: GST Tag, His Tag
Expression: Baculovirus
Kinase Family: CDK and CHK Kinase Family
Protein Form: Full Length, Recombinant
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% Glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

Documents

Manuals & protocols