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PDGFRA [V561D] Recombinant Human Protein

Catalog number:  PV4680

Related applications:

Protein Biology

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Description

PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. The PDGFRA V561D mutation is observed in gastrointestinal stromal tumors (GIST).
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_006197, V561D
Assay Entry: Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical europium phospho-specific activity, Biochemical binding/kinetic
Kinase Group: Tyrosine Kinases
Shipping Condition: Dry Ice
System Compatibility: LanthaScreen® Antibody, LanthaScreen® Substrate, Zin-LYTE™
Target Entry: PDGFRA V561D
Target Gene: platelet-derived growth factor receptor, alpha polypeptide
Expression System: Baculovirus
Protein Family: Kinases & Inhibitors
Protein Form: Recombinant, Cytoplasmic
Protein Subtype: Receptor Tyrosine Kinases
Research Category: Signal Transduction
Species: Human
Validated Application: Kinase Assay
Molecular Weight: 89.8 kDa
Gene Alias: PDGFRA V561D, PDGFR alpha
KinaseFamily: PDGFR Kinase Family
Protein Length: aa 550-1089; V561D
Protein Tag: GST Tag

Contents & storage

Storage Buffer: 50 mM Tris, pH 7.5, 150 mM NaCl, 0.02% Triton X-100, 0.5 mM EDTA, 2 mM DTT, 50 % Glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.