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PDGFRA [V561D] Recombinant Human Protein

Catalog number: PV4680

 Related applications: Protein Assays and Analysis | Target & Lead Identification & Validation

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Description

PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. The PDGFRA V561D mutation is observed in gastrointestinal stromal tumors (GIST).
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Species: Human
Target Gene: platelet-derived growth factor receptor, alpha polypeptide
Gene Aliases: PDGFRA V561D, PDGFR alpha
Kinase Group: Tyrosine Kinases
Product Size: 10 µg
Protein Family: Kinases & Inhibitors
Protein Subtype: Receptor Tyrosine Kinases
Accession Number: NP_006197, V561D
Molecular Weight: 89.8 kDa
Research Category: Signal Transduction
System Compatibility: LanthaScreen® Substrate, LanthaScreen® Antibody, Z'-LYTE™
Protein Tag or Fusion: GST Tag
Validated Application: Kinase Assay
Protein Length or Portion (a.a.): aa 550-1089; V561D
Expression: Baculovirus
Kinase Family: PDGFR Kinase Family
Protein Form: Recombinant, Cytoplasmic
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 50 mM Tris, pH 7.5, 150 mM NaCl, 0.02% Triton X-100, 0.5 mM EDTA, 2 mM DTT, 50 % Glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

Documents

Manuals & protocols