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Thermo Scientific™
FRAP1 (mTOR) Recombinant Human Protein
Catalog number: PV4754
Thermo Scientific™
FRAP1 (mTOR) Recombinant Human Protein
Catalog number: PV4754
Quantity
-
Quantity
| Catalog Number | Unit Size | Price (USD) | Availability | Quantity | |
|---|---|---|---|---|---|
| PV4754 | 1 mg | Contact Us › | - | - | |
| PR8683B | 100 µg | Price: 3,685.00 Your Price: | - |
Product Overview
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Additional Information
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FRAP1 (mTOR) is a serine⁄threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR⁄PI3-kinase⁄AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NP_004949.1
Molecular Weight
163.9 kDa
Quantity
1 mg
Gene Alias
FRAP1 (mTOR)
KinaseFamily
PIKK Kinase Family
Protein Length
aa 1360-2549
Host Species
Insect
Recombinant
Yes
Protein Tag
GST Tag
Kinase Group
Ser⁄Thr Kinases: Atypical
Shipping Condition
Dry Ice
System Compatibility
LanthaScreen™ Antibody, LanthaScreen™ Substrate, Zin-LYTE™
Target Entry
mTOR, FRAP1
Target Gene
FK506 binding protein 12-rapamycin associated protein 1
Expression System
Baculovirus
Protein Family
Kinases & Inhibitors
Protein Form
Recombinant, Catalytic
Form
Liquid
Protein Subtype
Serine/Threonine Kinases
Validated Application
Kinase Assay
Species
Human
Research Category
Drug Discovery: Oncology, Signal Transduction
Contents & Storage
Storage Buffer: 50 mM Tris, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.1% Polysorbate 20, 2 mM DTT, 50% Glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.