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EIF2AK2 (PKR) Recombinant Human Protein

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Description

EIF2AK2 (PKR) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses. EIF2AK2 plays a key role in antiviral defense mediated through its direct activation by double-stranded RNA produced by viral infection.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Research Category: Drug Development
Accession Number: NP_002750.1
Form: Frozen
Gene Aliases: EIF2AK2 (PKR)
Kinase Group: Ser⁄Thr Kinases: Other
Molecular Weight: 62.2 kDa
Product Size: 1 mg
Protein Length or Portion (a.a.): aa 252-551
Species: Human
Validated Application: Kinase Assay
Protein Tag or Fusion: GST Tag
Expression: Baculovirus
Kinase Family: PEK Kinase Family
Protein Form: Catalytic
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 50 mM Tris, pH 7.5, 50% glycerol, 0.5 mM EDTA, 0.02% Triton X-100, 150 mM NaCl, 2 mM DTT
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

Documents

Manuals & protocols