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LRRK2 Recombinant Human Protein

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Description

LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in this gene have been associated with Parkinson's disease.

Related Links:
LRRK2 tools for advancing Parkinson's disease research
Kinase protein portfolio
LanthaScreen® Eu Kinase Binding Assay
LanthaScreen® Activity Assay
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_940980.2
Expression: Baculovirus
Gene Aliases: LRRK2
Gene ID: 120892
Kinase Family: LRRK Kinase Family
Kinase Group: Ser⁄Thr Kinases: TKL Group
Molecular Weight: 204.9 kDa
Product Size: 10 µg
Protein Family: Kinases & Inhibitors
Protein Form: Catalytic,Recombinant
Protein Length or Portion (a.a.): aa 970-2527
Protein Subtype: Serine⁄Threonine Kinases
Protein Tag or Fusion: GST Tag
Research Category: Neurobiology,Signal Transduction
Shipping Condition: Dry Ice
Species: Human
System Compatibility: Adapta™,LanthaScreen® Antibody,LanthaScreen® Substrate
Target Gene: Leucine-rich repeat kinase 2
Validated Application: Kinase Assay

Contents & storage

Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Polysorbate 20, 2 mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.