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ACVRL1 (ALK1) Recombinant Human Protein

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Activin A receptor type II-like 1 (ACVRL1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands. ACVRL1, similar to other type 1 receptors, has a conserved serine-threonine kinase subdomain, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. Mutations in ACVRL1 are associated with hemorrhagic telangiectasia type 2.
For Research Use Only. Not for use in diagnostic procedures.


Accession Number: NP_000011.2
Assay Entry: Biochemical binding/kinetic
Kinase Group: Ser⁄Thr Kinases: TKL Group
Shipping Condition: Dry Ice
Target Entry: ACVRL1 (ALK1)
Target Gene: activin A receptor type II-like 1
Expression System: Baculovirus
Protein Family: Kinases & Inhibitors
Protein Form: Recombinant, Catalytic
Protein Subtype: Serine⁄Threonine Kinases
Research Category: Signal Transduction
Species: Human
Validated Application: Kinase Assay
Gene ID (Entrez): 94
Molecular Weight: 68.9 kDa
Gene Alias: ACVRL1 (ALK1)
KinaseFamily: STKR Kinase Family
Protein Length: aa 139-503
Protein Tag: GST Tag

Contents & storage

Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Polysorbate 20, 2 mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.