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MAP3K14 (NIK) Recombinant Human Protein

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Description

MAP3K14 (NIK) is structurally related to MAP3Ks. MAP3K14 phosphorylates and activates CHUK (IKKalpha) and IKBKB (IKK beta), which in turn phosphorylate IkB-alpha, releasing NF-KappaB leading to up-regulation of inflammatory response genes.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Protein Family: Kinases & Inhibitors
Research Category: Signal Transduction
Accession Number: NP_003945.2
Gene Aliases: MAP3K14 (NIK)
Gene ID: 9020
Kinase Group: Ser⁄Thr Kinases: STE Group
Molecular Weight: 96.9 kDa
Product Size: 10 µg
Protein Length or Portion (a.a.): aa 318-947
Protein Subtype: Serine⁄Threonine Kinases
Species: Human
Target Gene: mitogen-activated protein kinase kinase kinase 14
Validated Application: Kinase Assay
Protein Tag or Fusion: GST Tag
Expression: Baculovirus
Kinase Family: STE Unique Kinase Family
Protein Form: Catalytic, Recombinant
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.02% Trition X-100, 0.5 mM EDTA, 2 mM DTT, 50% Glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

Documents

Manuals & protocols