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MAP3K14 (NIK) Recombinant Human Protein

Catalog number:  PV4902

Related applications:

Protein Assays and Analysis

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Description

MAP3K14 (NIK) is structurally related to MAP3Ks. MAP3K14 phosphorylates and activates CHUK (IKKalpha) and IKBKB (IKK beta), which in turn phosphorylate IkB-alpha, releasing NF-KappaB leading to up-regulation of inflammatory response genes.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_003945.2
Assay Entry: Biochemical binding/kinetic
Kinase Group: Ser⁄Thr Kinases: STE Group
Shipping Condition: Dry Ice
Target Entry: MAP3K14
Target Gene: mitogen-activated protein kinase kinase kinase 14
Expression System: Baculovirus
Protein Family: Kinases & Inhibitors
Protein Form: Recombinant, Catalytic
Protein Subtype: Serine⁄Threonine Kinases
Research Category: Signal Transduction
Species: Human
Validated Application: Kinase Assay
Gene ID (Entrez): 9020
Molecular Weight: 96.9 kDa
Gene Alias: MAP3K14 (NIK)
KinaseFamily: STE Unique Kinase Family
Protein Length: aa 318-947
Protein Tag: GST Tag

Contents & storage

Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.02% Trition X-100, 0.5 mM EDTA, 2 mM DTT, 50% Glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.