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EIF2AK3 (PERK) Recombinant Human Protein

Catalog number:  PV5106

Related applications:

Pharma & Biopharma

| Protein Assays and Analysis

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Description

EIF2AK3 (PERK) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses, leading to a decrease in protein sythesis. In the case of EIF2AK3, signaling is initiated by misfolded proteins in the ER.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_004827.3
Assay Entry: Biochemical terbium phospho-specific activity
Kinase Group: Ser⁄Thr Kinases: Other
Shipping Condition: Dry Ice
System Compatibility: LanthaScreen® Antibody, LanthaScreen® Substrate
Target Entry: EIF2AK3
Target Gene: eukaryotic translation initiation factor 2-alpha kinase 3
Expression System: Baculovirus
Protein Family: Kinases & Inhibitors
Protein Form: Recombinant, Catalytic
Protein Subtype: Serine⁄Threonine Kinases
Research Category: Signal Transduction
Species: Human
Validated Application: Kinase Assay
Gene ID (Entrez): 9451
Molecular Weight: 93.6 kDa
Gene Alias: EIF2AK3 (PERK)
KinaseFamily: PEK Kinase Family
Protein Length: aa 536-1116
Protein Tag: GST Tag

Contents & storage

Storage Buffer: 50 mM Tris, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.