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EIF2AK3 (PERK) Recombinant Human Protein

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Description

EIF2AK3 (PERK) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses, leading to a decrease in protein sythesis. In the case of EIF2AK3, signaling is initiated by misfolded proteins in the ER.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Protein Family: Kinases & Inhibitors
Research Category: Signal Transduction
Accession Number: NP_004827.3
Gene Aliases: EIF2AK3 (PERK)
Gene ID: 9451
Kinase Group: Ser⁄Thr Kinases: Other
Molecular Weight: 93.6 kDa
Product Size: 10 µg
Protein Length or Portion (a.a.): aa 536-1116
Protein Subtype: Serine⁄Threonine Kinases
Species: Human
System Compatibility: LanthaScreen® Antibody, LanthaScreen® Substrate
Target Gene: eukaryotic translation initiation factor 2-alpha kinase 3
Validated Application: Kinase Assay
Protein Tag or Fusion: GST Tag
Expression: Baculovirus
Kinase Family: PEK Kinase Family
Protein Form: Catalytic, Recombinant
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 50 mM Tris, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

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