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PIK3C3 (hVPS34) Recombinant Human Protein

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Description

PIK3C3 (hVPS34) is the sole class III member of the PI3 Kinase family. PIK3C3 phosphorylates phosphatidylinositol (PI) to produce phosphatidylinositol 3-phosphate [PI(3)P], which recruits downstream effectors containing FYVE and Phox domains to membranes. PIK3C3 is involved in coupling nutrient signaling to mTOR and also plays a role in autophagy and intracellular trafficking.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Protein Family: Kinases & Inhibitors
Research Category: Signal Transduction
Accession Number: NP_002638.2
Expression: Baculovirus
Gene Aliases: PIK3C3 (hVPS34)
Gene ID: 5289
Kinase Group: Lipid Kinases
Molecular Weight: 129 kDa
Product Size: 20 µg
Protein Subtype: Lipid Kinases
Protein Tag or Fusion: GST Tag
Species: Human
System Compatibility: Adapta™
Target Gene: phosphoinositide-3-kinase, class 3
Validated Application: Kinase Assay
Kinase Family: PI3 Kinase Family
Protein Form: Full Length, Recombinant
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 50 mM Tris, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% CHAPS, 2 mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

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