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PIK3C3 (hVPS34) is the sole class III member of the PI3 Kinase family. PIK3C3 phosphorylates phosphatidylinositol (PI) to produce phosphatidylinositol 3-phosphate [PI(3)P], which recruits downstream effectors containing FYVE and Phox domains to membranes. PIK3C3 is involved in coupling nutrient signaling to mTOR and also plays a role in autophagy and intracellular trafficking.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NP_002638.2
Gene ID (Entrez)
5289
Molecular Weight
129 kDa
Quantity
20 µg
Gene Alias
PIK3C3 (hVPS34)
KinaseFamily
PI3 Kinase Family
Recombinant
Yes
Protein Tag
GST Tag
Assay Entry
Biochemical ADP accumulation
Kinase Group
Lipid Kinases
Shipping Condition
Dry Ice
System Compatibility
Adapta™
Target Entry
PIK3C3
Target Gene
phosphoinositide-3-kinase, class 3
Expression System
Baculovirus
Protein Family
Kinases & Inhibitors
Protein Form
Recombinant, Full Length
Protein Subtype
Lipid Kinases
Validated Application
Kinase Assay
Species
Human
Research Category
Signal Transduction
Contents & Storage
Storage Buffer: 50 mM Tris, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% CHAPS, 2 mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.