For order quantities > 1, multiple lots may be used to fulfill the order. If you require a single lot, please email discoverysciences@lifetech.com to ensure your needs are accommodated

88 more kinases now available to order! See the complete list.

SPHK1 Recombinant Human Protein

Catalog number:  PV5214

Related applications:

Pharma & Biopharma

| Protein Assays and Analysis

Back to top

Description

SPHK1, along with SPHK2, catalyzes the phosphorylation of sphingosine producing the signalling molecule sphingosine-1-phosphate (S1P). S1P signals through G-protein coupled receptors and controls diverse cellular processes. Inhibitors of SPHKs are viewed as potential therapuetics for the treatment of cancer.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_068807.2
Assay Entry: Biochemical ADP accumulation
Kinase Group: Lipid Kinases
Protein Form: Full Length, Recombinant
Research Category: Oncology, Signal Transduction
Shipping Condition: Dry Ice
Species: Human
System Compatibility: Adapta™
Target Entry: SPHK1
Target Gene: sphingosine kinase 1
Molecular Weight: 71.4 kDa
Protein Subtype: Lipid Kinases
Gene Alias: SPHK1
Validated Application: Kinase Assay
Protein Family: Kinases & Inhibitors
Expression System: Baculovirus
KinaseFamily: SPHK and DGCK Kinase Family
Protein Tag: GST Tag

Contents & storage

Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.02% Triton X-100, 0.5 mM EDTA, 2 mM DTT, 50% Glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.