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SPHK1 Recombinant Human Protein

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Description

SPHK1, along with SPHK2, catalyzes the phosphorylation of sphingosine producing the signalling molecule sphingosine-1-phosphate (S1P). S1P signals through G-protein coupled receptors and controls diverse cellular processes. Inhibitors of SPHKs are viewed as potential therapuetics for the treatment of cancer.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Protein Family: Kinases & Inhibitors
Research Category: Oncology, Signal Transduction
Accession Number: NP_068807.2
Expression: Baculovirus
Gene Aliases: SPHK1
Kinase Group: Lipid Kinases
Molecular Weight: 71.4 kDa
Product Size: 20 µg
Protein Subtype: Lipid Kinases
Protein Tag or Fusion: GST Tag
Species: Human
System Compatibility: Adapta™
Target Gene: sphingosine kinase 1
Validated Application: Kinase Assay
Kinase Family: SPHK and DGCK Kinase Family
Protein Form: Full Length, Recombinant
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.02% Triton X-100, 0.5 mM EDTA, 2 mM DTT, 50% Glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

Documents

Manuals & protocols