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SPHK1 Recombinant Human Protein

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SPHK1, along with SPHK2, catalyzes the phosphorylation of sphingosine producing the signalling molecule sphingosine-1-phosphate (S1P). S1P signals through G-protein coupled receptors and controls diverse cellular processes. Inhibitors of SPHKs are viewed as potential therapuetics for the treatment of cancer.
For Research Use Only. Not for use in diagnostic procedures.


Species: Human
Expression: Baculovirus
Target Gene: sphingosine kinase 1
Gene Aliases: SPHK1
Kinase Group: Lipid Kinases
Product Size: 20 µg
Protein Family: Kinases & Inhibitors
Protein Subtype: Lipid Kinases
Accession Number: NP_068807.2
Molecular Weight: 71.4 kDa
Research Category: Signal Transduction, Oncology
System Compatibility: Adapta™
Protein Tag or Fusion: GST Tag
Validated Application: Kinase Assay
Kinase Family: SPHK and DGCK Kinase Family
Protein Form: Full Length, Recombinant
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.02% Triton X-100, 0.5 mM EDTA, 2 mM DTT, 50% Glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.


Manuals & protocols