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Thermo Scientific™
SPHK2 Recombinant Human Protein
Catalog number: PV5216
Thermo Scientific™
SPHK2 Recombinant Human Protein
Catalog number: PV5216
Product Overview
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Additional Information
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SPHK2, along with SPHK1, catalyzes the phosphorylation of sphingosine producing the signalling molecule sphingosine-1-phosphate (S1P). S1P signals through G-protein coupled receptors and controls diverse cellular processes. Inhibitors of SPHKs are viewed as potential therapuetics for the treatment of cancer.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NP_064511.2
Molecular Weight
96.7 kDa
Purity
90% by SDS-PAGE
Quantity
20 µg
Gene Alias
SPHK2
KinaseFamily
SPHK and DGCK Kinase Family
Host Species
Insect
Recombinant
Yes
Protein Tag
GST Tag
Assay Entry
Biochemical ADP accumulation
Kinase Group
Lipid Kinases
Shipping Condition
Dry Ice
System Compatibility
Adapta™
Target Entry
SPHK2
Target Gene
sphingosine kinase 2
Expression System
Baculovirus
Protein Family
Kinases & Inhibitors
Protein Form
Recombinant, Full Length
Form
Liquid
Protein Subtype
Lipid Kinases
Validated Application
Kinase Assay
Species
Human
Research Category
Drug Discovery: Oncology, Signal Transduction
Contents & Storage
Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.02% Trition X-100, 0.5 mM EDTA, 2 mM DTT, 50% Glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.