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Thermo Scientific™

SPHK2 Recombinant Human Protein

Catalog number:  PV5216

Related applications:

Protein Assays and Analysis

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Description

SPHK2, along with SPHK1, catalyzes the phosphorylation of sphingosine producing the signalling molecule sphingosine-1-phosphate (S1P). S1P signals through G-protein coupled receptors and controls diverse cellular processes. Inhibitors of SPHKs are viewed as potential therapuetics for the treatment of cancer.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_064511.2
Assay Entry: Biochemical ADP accumulation
Kinase Group: Lipid Kinases
Shipping Condition: Dry Ice
System Compatibility: Adapta™
Target Entry: SPHK2
Target Gene: sphingosine kinase 2
Expression System: Baculovirus
Protein Family: Kinases & Inhibitors
Protein Form: Full Length, Recombinant
Protein Subtype: Lipid Kinases
Research Category: Oncology, Signal Transduction
Species: Human
Validated Application: Kinase Assay
Molecular Weight: 96.7 kDa
Gene Alias: SPHK2
KinaseFamily: SPHK and DGCK Kinase Family
Protein Tag: GST Tag

Contents & storage

Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.02% Trition X-100, 0.5 mM EDTA, 2 mM DTT, 50% Glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.