Search Thermo Fisher Scientific
Product Overview
Figures
Videos
Recommendations
Recommendations
Documents
FAQ
Citations & References
Additional Information
Recommendations
PDK4 (PDHK4), along with the other PDHKs, regulates glucose metabolism by phosphorylating the E1 alpha subunit of the mitochondrial pyruvate dehydrogenase complex. Inhhibition of PDHKs is viewed as a potential therapeutic treament for type II diabetes.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NP_002603.1
Gene ID (Entrez)
PDK4
Molecular Weight
73.9 kDa
Quantity
10 µg
Gene Alias
PDK-4 (PDKH4)
Gene Symbol
PDK4
KinaseFamily
PDHK Kinase Family
Protein Length
Full-length
Recombinant
Yes
Protein Tag
GST Tag
Mass
10 µg
Kinase Group
Ser⁄Thr Kinases: Atypical
Reactivity
Human
Shipping Condition
Dry Ice
System Compatibility
Adapta™ Universal Kinase Assay
Tag Position
N-Terminal
Target Gene
PDK4
Expression System
Baculovirus
Protein Family
Kinases & Inhibitors
Protein Form
Recombinant, Full Length
Form
Liquid
Protein Subtype
Serine/Threonine Kinases
Validated Application
Kinase Assay
Species
Human
Research Category
Signal Transduction
Contents & Storage
50 mM Tris pH 7.5, 150 mM NaCl, 0.02% Trition X-100, 0.5 mM EDTA, 2 mM DTT, 50% Glycerol.
Kinase proteins are shipped on dry ice. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
Kinase proteins are shipped on dry ice. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.