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PDK4 (PDKH4) Recombinant Human Protein

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Description

PDK4 (PDHK4), along with the other PDHKs, regulates glucose metabolism by phosphorylating the E1 alpha subunit of the mitochondrial pyruvate dehydrogenase complex. Inhhibition of PDHKs is viewed as a potential therapeutic treament for type II diabetes.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Protein Family: Kinases & Inhibitors
Research Category: Signal Transduction
Accession Number: NP_002603.1
Gene Aliases: PDK-4 (PDKH4)
Gene Symbol: PDK4
Kinase Group: Ser⁄Thr Kinases: Atypical
Mass: 10 µg
Molecular Weight: 73.9 kDa
Product Size: 10 µg
Protein Subtype: Serine⁄Threonine Kinases
Reactivity: Human
Species: Human
System Compatibility: Adapta™ Universal Kinase Assay
Target Gene: PDK4
Validated Application: Kinase Assay
Protein Tag or Fusion: GST Tag
Tag Position: N-Terminal
Expression: Baculovirus
Kinase Family: PDHK Kinase Family
Protein Form: Full Length, Recombinant
Shipping Condition: Dry Ice

Contents & storage

50 mM Tris pH 7.5, 150 mM NaCl, 0.02% Trition X-100, 0.5 mM EDTA, 2 mM DTT, 50% Glycerol.

Kinase proteins are shipped on dry ice. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

Documents

Manuals & protocols