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Thermo Scientific™

LRRK2 [I2020T] Human Protein

Catalog number:  PV5854

Related applications:

Protein Assays and Analysis

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Description

LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in this gene have been associated with Parkinson's disease, including the I2020T mutation in the kinase catalytic domain.

Related Links:
LRRK2 tools for advancing Parkinson's disease research
Kinase protein portfolio
LanthaScreen® Eu Kinase Binding Assay
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For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_940980.2
Assay Entry: Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Kinase Group: Ser⁄Thr Kinases: TKL Group
Shipping Condition: Dry Ice
System Compatibility: LanthaScreen®, Adapta™
Tag Position: N-Terminal
Target Entry: LRRK2 I2020T
Target Gene: LRRK2 I2020T
Expression System: Baculovirus
Form: Frozen
Protein Family: Kinases & Inhibitors
Protein Form: Catalytic
Protein Subtype: Serine⁄Threonine Kinases
Research Category: Signal Transduction, Neurobiology
Species: Human
Validated Application: Kinase Assay
Molecular Weight: 205 kDa
Gene Alias: LRRK2 I2020T
KinaseFamily: LRRK Kinase Family
Protein Tag: GST Tag

Contents & storage

Kinase proteins are shipped on dry ice and should be stored at -80°C.