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LRRK2 [I2020T] Human Protein

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Description

LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in this gene have been associated with Parkinson's disease, including the I2020T mutation in the kinase catalytic domain.

Related Links:
LRRK2 tools for advancing Parkinson's disease research
Kinase protein portfolio
LanthaScreen® Eu Kinase Binding Assay
LanthaScreen® Activity Assay
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_940980.2
Expression: Baculovirus
Form: Frozen
Gene Aliases: LRRK2 I2020T
Kinase Family: LRRK Kinase Family
Kinase Group: Ser⁄Thr Kinases: TKL Group
Molecular Weight: 205 kDa
Product Size: 10 µg
Protein Family: Kinases & Inhibitors
Protein Form: Catalytic
Protein Subtype: Serine⁄Threonine Kinases
Protein Tag or Fusion: GST Tag
Research Category: Neurobiology,Signal Transduction
Shipping Condition: Dry Ice
Species: Human
System Compatibility: Adapta™,LanthaScreen®
Tag Position: N-Terminal
Target Gene: LRRK2 I2020T
Validated Application: Kinase Assay

Contents & storage

Kinase proteins are shipped on dry ice and should be stored at -80°C.