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EIF2AK1 (HRI) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses, leading to a decrease in protein sythesis. In the case of EIF2AK1, signaling is initiated by low levels of heme.
For Research Use Only. Not for use in diagnostic procedures.
Ser⁄Thr Kinases: Other
Kinases & Inhibitors
PEK Kinase Family
Contents & Storage
Kinase proteins are shipped on dry ice and should be stored at -80°C.