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LRRK2 [D1994A] Human Protein

Catalog number: PV6051

LRRK2 [D1994A] Human Protein

Catalog number: PV6051
Catalog Number
PV6051
Unit Size
10 µg
Price (USD)
438.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
100 µg
Price (USD)
2,305.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
1 mg
Price (USD)
10,940.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
PV605110 µg
438.00
Your Price:
***
PR9102A100 µg
2,305.00
Your Price:
***
PV60521 mg
10,940.00
Your Price:
***
Product Overview
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Additional Information
Recommendations
LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Certain mutations (e.g. I2020T, G2019S, and R1441C) in this gene have been associated with Parkinson's disease. D1994A is an artificial mutation that renders the kinase catalytically inactive and thus serves as a useful control for activity assays, especially when testing novel substrates.

Related Links:
LRRK2 tools for advancing Parkinson's disease research
Kinase protein portfolio
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For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number
NP_940980.2
Assay Entry
Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Kinase Group
Ser⁄Thr Kinases: TKL Group
Shipping Condition
Dry Ice
Target Entry
LRRK2 D1994A
Target Gene
LRRK2
Expression System
Baculovirus
Protein Family
Kinases & Inhibitors
Protein Form
Catalytic
Protein Subtype
Serine⁄Threonine Kinases
Research Category
Signal Transduction, Neurobiology
Species
Human
Validated Application
Kinase Assay
Gene ID (Entrez)
120892
Molecular Weight
205 kDa
Quantity
10 µg
Gene Alias
LRRK2 D1994A
KinaseFamily
LRRK Kinase Family
Protein Length
aa 970-2527
Protein Tag
GST Tag

Contents & Storage

Kinase proteins are shipped on dry ice and should be stored at -80°C.

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