Thermo Scientific™

MERTK (cMER) [A708S] Recombinant Human Protein

Catalog number: PV6326
Thermo Scientific™

MERTK (cMER) [A708S] Recombinant Human Protein

Catalog number: PV6326
Catalog Number
PV6326
Unit Size
100 µg
Price (USD)
1,546.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
10 µg
Price (USD)
451.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
1 mg
Price (USD)
6,920.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
PV6326100 µg
1,546.00
Your Price:
***
PV632510 µg
451.00
Your Price:
***
PV63271 mg
6,920.00
Your Price:
***
Product Overview
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MERTK (c-MER) is a member of the TYRO3/AXL/MER (TAM) receptor kinase family which encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Cytokine-dependent activation of TAM signaling diverts a proinflammatory pathway to provide an intrinsic feedback inhibitor of both TLR- and cytokine-driven immune responses. MERTK is essential regulators of mammalian spermatogenesis. Mutations in MERTK gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). Recombinant human MERTK A708S (578-872) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

• Validated in LanthaScreen® Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes available for convenient use

Related Product:
LanthaScreen® Eu Kinase Binding Assay
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Kinase Group
Receptor Tyrosine Kinase
Expression System
Baculovirus
Form
Liquid
Protein Family
Growth Factors & Receptors, Kinases & Inhibitors
Protein Form
Recombinant
Species
Human
Validated Application
Kinase Assay
Molecular Weight
60.2 kDa
Quantity
100 µg
Gene Alias
MERTK
Protein Length
aa 578-872
Recombinant
Yes
Protein Tag
GST Tag

Contents & Storage

Storage Buffer: 50 mM Tris-HCl pH 7.5, 150 mM NaCl, 0.25 mM DTT, 10 mM glutathione, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol

Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.

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Citations & References