MAP4K1 (HPK1) Recombinant Human Protein

Catalog number:  PV6357

Related applications:

Pharma & Biopharma

| Protein Assays and Analysis

Back to top

Description

MAP4K1 (also known as HPK1) or Hematopoietic progenitor kinase 1 is a hematopoietic cell-restricted member of the Ste20 serine/threonine kinase super family. MAP4K1 is a tissue-specific upstream activator of the MEKK/JNK/SAPK signaling pathway. MAP4K1 diminishes T cell receptor (TCR) signaling activity and T cell proliferation by phosphorylating the adaptor protein SLP-76. Recombinant human MAP4K1 (1-346) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

• Validated in LanthaScreen® Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes available for convenient use

Related Product:
LanthaScreen® Eu Kinase Binding Assay
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Kinase Group: Serine/Threonine Kinase
Species: Human
Validated Application: Kinase Assay
Molecular Weight: 65.0 kDa
Quantity: 1mg
Gene Alias: MAP4K1
Protein Length: aa 1-346
Protein Tag: GST Tag, His Tag

Contents & storage

Storage Buffer: 50 mM Tris-HCl pH 7.5, 150 mM NaCl, 0.25 mM DTT, 10 mM glutathione, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol

Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.