Thermo Scientific™

STK38 (NDR) Recombinant Human Protein

Catalog number: PV6370
Thermo Scientific™

STK38 (NDR) Recombinant Human Protein

Catalog number: PV6370
Catalog Number
PV6370
Unit Size
10 µg
Price (USD)
Price: 500.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
100 µg
Price (USD)
Price: 1,716.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
1 mg
Price (USD)
Price: 7,660.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
PV637010 µg
Price: 500.00
Your Price:
***
PV6371100 µg
Price: 1,716.00
Your Price:
***
PV63721 mg
Price: 7,660.00
Your Price:
***
Product Overview
Figures
Videos
Recommendations
Recommendations
Documents
FAQ
Citations & References
Additional Information
Recommendations
STK38 (also known as NDR) or Nuclear Dbf2-related protein is a serine/threonine kinase in the subgroup of the AGC kinase family that is regulated by Mob proteins. Fas and TNFα receptor stimulation activates human STK38 by promoting phosphorylation at the hydrophobic motif. NDR acts as a novel pro-apoptotic kinase, and is a key member of the RASSF1A/MST1 signaling cascade. STK38 is crucial for the fidelity of mitotic chromosome alignment in mammalian cells. STK38 is incorporated into the HIV-1 particles and is cleaved by the HIV-1 protease. STK38-driven centrosome duplication requires Cdk2 activity, and Cdk2-induced centrosome amplification is affected upon reduction of STK38 activity. Full-length recombinant human STK38 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

• Validated in LanthaScreen™ Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes available for convenient use

Related Product:
LanthaScreen™ Eu Kinase Binding Assay
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Molecular Weight
80.5 kDa
Quantity
10 µg
Gene Alias
NDR1, STK38
Host Species
Insect
Recombinant
Yes
Protein Tag
GST Tag
Assay Entry
Biochemical binding/kinetic
Kinase Group
Serine/Threonine Kinase
Target Entry
STK38 (NDR)
Expression System
Baculovirus
Protein Family
Kinases & Inhibitors
Protein Form
Recombinant, Full Length
Form
Liquid
Protein Subtype
Serine/Threonine Kinases
Validated Application
Kinase Assay
Species
Human
Research Category
Drug Discovery: Apoptosis, Cell Cycle, Signal Transduction

Contents & Storage

Storage Buffer: 50 mM Tris-HCl pH 7.5, 150 mM NaCl, 0.25 mM DTT, 10 mM glutathione, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol

Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.