Thermo Scientific™

NUAK2 Recombinant Human Protein

Catalog number: PV6378
Thermo Scientific™

NUAK2 Recombinant Human Protein

Catalog number: PV6378
Catalog Number
PV6378
Unit Size
1 mg
Price (USD)
6,920.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
10 µg
Price (USD)
449.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
100 µg
Price (USD)
1,542.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
PV63781 mg
6,920.00
Your Price:
***
PV637610 µg
449.00
Your Price:
***
PV6377100 µg
1,542.00
Your Price:
***
Product Overview
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Additional Information
Recommendations
NUAK2 or SNF1/AMP kinase-related kinase (SNARK) is a member of the NUAK family of SNF1-like kinase 2. NUAK2 is activated by muscle contraction and is a unique mediator of contraction-stimulated glucose transport in skeletal muscle (1). NUAK2 is involved in cellular stress responses linked to obesity and type 2 diabetes. NUAK2 shows kinase activity against a synthetic test peptide and the activity in keratinocytes is increased by AMP and 5-amino-4-imidazolecarboxamide riboside, implying that AMPK kinase-dependent pathway can activate NAUK2. Glucose deprivation also increases NAUK2 activity in baby hamster kidney fibroblasts. Recombinant full-length human NUAK2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

• Validated in LanthaScreen® Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes available for convenient use

Related Product:
LanthaScreen® Eu Kinase Binding Assay
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Kinase Group
Serine/Threonine Kinase
Expression System
Baculovirus
Form
Liquid
Protein Form
Recombinant
Species
Human
Validated Application
Kinase Assay
Molecular Weight
96.3 kDa
Quantity
1 mg
Gene Alias
SNARK, FLJ90349, DKFZP434J037, DKFZp686F01113
Recombinant
Yes
Protein Tag
GST Tag

Contents & Storage

Storage Buffer: 50 mM Tris-HCl pH 7.5, 150 mM NaCl, 0.25 mM DTT, 10 mM glutathione, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol

Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.

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Frequently asked questions (FAQs)

Citations & References