Thermo Scientific™

CDK14 (PFTK1)/cyclin Y Recombinant Human Protein

Catalog number: PV6382
Thermo Scientific™

CDK14 (PFTK1)/cyclin Y Recombinant Human Protein

Catalog number: PV6382
Catalog Number
PV6382
Unit Size
10 µg
Price (USD)
Price: 499.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
100 µg
Price (USD)
Price: 1,746.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
1 mg
Price (USD)
Price: 7,680.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
PV638210 µg
Price: 499.00
Your Price:
***
PV6383100 µg
Price: 1,746.00
Your Price:
***
PV63841 mg
Price: 7,680.00
Your Price:
***
Product Overview
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Additional Information
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CDK14 (PFTK1)/cyclin Y is a member of the CDC2-related protein kinase family which is expressed primarily in the postnatal and adult nervous system. CDK14 is expressed at high levels in brain, pancreas, kidney, heart, testis, and ovary. CDK14 amino acid residue ser119 is required for its interaction with all four 14-3-3 isoforms, while ser120 may contribute slightly to CDK14 binding. CDK14 acts as a cyclin-dependent kinase that regulates cell cycle progression and cell proliferation. Overexpression of CDK14 predicts resistance to chemotherapy in patients with oesophageal squamous cell carcinoma. Recombinant human full-length CDK14 and Cyclin Y (2-end) were co-expressed by baculovirus in Sf9 insect cells using N-terminal GST tags.

• Validated in LanthaScreen™ Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes available for convenient use

Related Product:
LanthaScreen™ Eu Kinase Binding Assay
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Molecular Weight
77.0/65.5 kDa
Quantity
10 µg
Protein Length
aa Full, 2-end
Host Species
Insect
Recombinant
Yes
Protein Tag
GST Tag
Assay Entry
Biochemical binding/kinetic
Kinase Group
Serine/Threonine Kinase
Target Entry
CDK14 (PFTK1)/cyclin Y 
Expression System
Baculovirus
Protein Family
Kinases & Inhibitors
Protein Form
Recombinant
Form
Liquid
Protein Subtype
Serine/Threonine Kinases
Validated Application
Kinase Assay
Species
Human
Research Category
Drug Discovery: Cell Cycle & Proliferation, Signal Transduction

Contents & Storage

Storage Buffer: 50 mM Tris-HCl pH 7.5, 150 mM NaCl, 0.25 mM DTT, 10 mM glutathione, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol

Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.