SIK1 Recombinant Human Protein

Catalog number: PV6446

SIK1 Recombinant Human Protein

Catalog number: PV6446
Catalog Number
PV6446
Unit Size
100 µg
Price (USD)
1,546.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
10 µg
Price (USD)
451.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
1 mg
Price (USD)
6,920.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
PV6446100 µg
1,546.00
Your Price:
***
PV644510 µg
451.00
Your Price:
***
PV64471 mg
6,920.00
Your Price:
***
Product Overview
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SIK1 is a protein kinase that is involved in regulating AMPK-related kinases. This recombinant human SIK1 (1-303) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

• Validated in LanthaScreen® Kinase Binding Assay
• Protocols available for simple use and optimized performance

SIK1 may mediate the physiological effects of LKB1, including its tumour suppressor function. SIK1 is also involved in signaling by various proteins like STRAD, NUAK1, NUAK2, BRSK1, BRSK2, QIK, QSK, SIK, MARK1, MARK2, MARK3, MARK4, and MELK that are related to AMPK. Activation of SIK1 by phosphorylation on thr322 can lead to an increase in the catalytic activity of sodium/potassium ATPase alpha subunit at the plasma membrane. This results in an increase in intracellular sodium in intact mammalian cells.

Learn more about our kinase proteins >

Related Links:
LanthaScreen® Kinase Activity Assay
LanthaScreen® Eu Kinase Binding Assay
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number
NP_173354
Kinase Group
Serine/Threonine Kinase
Expression System
Baculovirus
Form
Liquid
Protein Form
Recombinant, Active, Catalytic
Research Category
Drug Development, Signal Transduction
Species
Human
Validated Application
Kinase Assay
Gene ID (Entrez)
150094
Molecular Weight
61 kDa
Quantity
100μg
Gene Alias
SNF1LK, MSK, SIK1
Protein Length
aa 1-303
Recombinant
Yes
Protein Tag
GST Tag

Contents & Storage

Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.1 mM PMSF, 0.25 mM DTT, 25% glycerol

Store at -68 to -85°C. After first use, aliquot and store to avoid multiple freeze-thaws.

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Frequently asked questions (FAQs)

Citations & References