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Highest antigen sequence indentity to the following orthologs: Mouse (88%), Rat (88%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-81955. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ELK3, ETS-domain protein (SRF accessory protein 2); ETS domain-containing protein Elk-3; ETS-related protein ERP; ETS-related protein NET; SAP-2; Serum response factor accessory protein 2; SRF accessory protein 2
Gene Aliases: ELK3; ERP; NET; SAP-2; SAP2
UniProt ID: (Human) P41970
Entrez Gene ID: (Human) 2004
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