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Invitrogen
Human SULT1A1 (aa 108-135) Control Fragment Recombinant Protein
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Product Details
RP-104452
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
HLPLALLPQTLLDQKVKVVYVARNAKDV
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (86%), Rat (86%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-111292. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. Members of the three groups comprising this superfamily (namely SULT1, SULT2 and SULT3) show selectivity to certain substrate compounds. SULT1A1 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1), also known as STP or STP1, is a 295 amino acid protein that localizes to the cytoplasm and belongs to the sulfotransferase family. Functioning as a homodimer that is expressed in brain, liver, skin and lung tissue, SULT1A1 catalyzes the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters and, via this catalytic activity, plays a role in the elimination of a variety of compounds from the body. Additionally, SULT1A1 may be involved in the activation of carcinogenic N-hydroxyarylamines, indicating a possible role in carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Aryl sulfotransferase 1; CSPS; HAST1/HAST2; MGC131921; MGC5163; OTTHUMP00000162568; OTTHUMP00000162569; P PST; P PST 1; P-PST 1; Phenol sulfotransferase 1; Phenol-sulfating phenol sulfotransferase 1; ST1A1; ST1A3; Sulfotransferase 1A1; sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1; Thermostable phenol sulfotransferase; thermostable phenol sulfotransferase1; Ts-PST
Gene Aliases: HAST1/HAST2; OK/SW-cl.88; P-PST; PST; ST1A1; ST1A3; STP; STP1; SULT1A1; TSPST1
UniProt ID: (Human) P50225
Entrez Gene ID: (Human) 6817
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