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Highest antigen sequence indentity to the following orthologs: Mouse (35%), Rat (35%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-65439. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DRIP92; MED16_i10; alternatively spliced; MED16_i11; alternatively spliced; MED16_i12; alternatively spliced; MED16_i13; alternatively spliced; MED16_i14; alternatively spliced; MED16_i15; alternatively spliced; MED16_i16; alternatively spliced; MED16_i17; alternatively spliced; MED16_i18; alternatively spliced; MED16_i19; alternatively spliced; MED16_i20; alternatively spliced; MED16_i21; alternatively spliced; MED16_i22; alternatively spliced; MED16_i23; alternatively spliced; MED16_i24; alternatively spliced; MED16_i25; alternatively spliced; MED16_i26; alternatively spliced; MED16_i27; alternatively spliced; MED16_i28; alternatively spliced; MED16_i29; alternatively spliced; MED16_i2; alternatively spliced; MED16_i30; alternatively spliced; MED16_i31; alternatively spliced; MED16_i32; alternatively spliced; MED16_i33; alternatively spliced; MED16_i34; alternatively spliced; MED16_i35; alternatively spliced; MED16_i3; alternatively spliced; MED16_i4; alternatively spliced; MED16_i5; alternatively spliced; MED16_i6; alternatively spliced; MED16_i7; alternatively spliced; MED16_i8; alternatively spliced; MED16_i9; alternatively spliced; Mediator complex subunit 16; Mediator of RNA polymerase II transcription subunit 16; Thyroid hormone receptor-associated protein 5; Thyroid hormone receptor-associated protein complex 95 kDa component; thyroid hormone receptor-associated protein, 95-kD subunit; Trap95; Vitamin D3 receptor-interacting protein complex 92 kDa component
Gene Aliases: DRIP92; GGNS; MED16; THRAP5; TRAP95
UniProt ID: (Human) Q9Y2X0
Entrez Gene ID: (Human) 10025
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