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Invitrogen
Human ZFYVE1 (aa 590-736) Control Fragment Recombinant Protein
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Product Details
RP-89066
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
IAPAYWRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCYEARNVQLAVTEAQVDDEGGTLIARKVGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILHCHNCRKEFSIKLSKHH
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-51768. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate (PtdIns(3)P)-containing membranes. This gene encodes a protein which contains two zinc-binding FYVE domains in tandem. This protein displays a predominantly Golgi, endoplasmic reticulum and vesicular distribution. Alternatively spliced transcript variants have been found for this gene, and they encode two isoforms with different sizes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Double FYVE-containing protein 1; phosphoinositide-binding protein SR3; protein phosphatase 1, regulatory subunit 172; SR3; Tandem FYVE fingers-1; tandem FYVE fingers-1 protein; Zinc finger FYVE domain-containing protein 1; zinc finger protein, subfamily 2A, member 1; zinc finger, FYVE domain containing 1
Gene Aliases: DFCP1; KIAA1589; PP10436; PPP1R172; SR3; TAFF1; ZFYVE1; ZNFN2A1
UniProt ID: (Human) Q9HBF4
Entrez Gene ID: (Human) 53349
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