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Invitrogen
Human LGALS3BP (aa 114-232) Control Fragment Recombinant Protein
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Product Details
RP-93676
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
RHERDAGVVCTNETRSTHTLDLSRELSEALGQIFDSQRGCDLSISVNVQGEDALGFCGHTVILTANLEAQALWKEPGSNVTMSVDAECVPMVRDLLRYFYSRRIDITLSSVKCFHKLAS
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (67%), Rat (67%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-51411. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 90K; Basement membrane autoantigen p105; Galectin-3-binding protein; L3 antigen; Lectin; Lectin galactoside-binding soluble 3-binding protein; mac-2 BP; Mac-2-binding protein; MAC2BP; serum protein 90K; transport and golgi organization 10 homolog B; Tumor-associated antigen 90K; unnamed protein product
Gene Aliases: 90K; BTBD17B; CyCAP; gp90; LGALS3BP; M2BP; MAC-2-BP; TANGO10B
UniProt ID: (Human) Q08380
Entrez Gene ID: (Human) 3959
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