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OriGene
NDEL1 Monoclonal Antibody (OTI1G7), TrueMAB™
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Product Details
TA503254S
Product Specifications
Species Reactivity
Dog,
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
OTI1G7
Immunogen
Full length human recombinant protein of human NDEL1 produced in HEk293 cell.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
30 µg
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a thiol-activated peptidase that is phosphorylated in M phase of the cell cycle. Phosphorylation regulates the cell cycle-dependent distribution of this protein, with a fraction of the protein bound strongly to centrosomes in interphase and localized to mitotic spindles in early M phase. Overall, this protein plays a role in nervous system development. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp451M0318; endooligopeptidase A; LIS1-interacting protein NUDEL; LIS1-interacting protein NUDEL; endooligopeptidase A; Mitosin-associated protein 1; mitosin-associated protein MITAP1; mNudE-L; nuclear disribution gene E like; nuclear distribution gene E-like homolog 1; Nuclear distribution protein nudE-like 1; nudE nuclear distribution E homolog-like 1; nudE nuclear distribution gene E homolog like 1; nudE nuclear distribution gene E homolog-like 1; NUDE-like protein; Protein mNudE-like; Protein Nudel; unnamed protein product
Gene Aliases: 2600006O07Rik; EOPA; MITAP1; mNudel; NDE1L1; NDE2; NDEL1; NUDE2; NUDEL
UniProt ID: (Human) Q9GZM8, (Rat) Q78PB6, (Mouse) Q9ERR1
Entrez Gene ID: (Human) 81565, (Dog) 489495, (Rat) 170845, (Mouse) 83431
establishment of mitotic spindle orientation
microtubule cytoskeleton organization
neuron migration
inner cell mass cell proliferation
proteolysis
microtubule nucleation
chromosome segregation
mitotic centrosome separation
retrograde axonal transport
regulation of neuron projection development
cell migration
cerebral cortex radially oriented cell migration
central nervous system neuron axonogenesis
neuron projection development
positive regulation of axon extension
vesicle transport along microtubule
positive regulation of axon regeneration
nuclear envelope disassembly
establishment of chromosome localization
centrosome localization
neurofilament cytoskeleton organization
canonical Wnt signaling pathway
neuron projection extension
nervous system development
insulin receptor signaling pathway
cell differentiation
lysosome localization
regulation of intracellular protein transport
positive regulation of GTPase activity
radial glia-guided pyramidal neuron migration
positive regulation of ruffle assembly
transport
multicellular organism development
activation of GTPase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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