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OriGene
PDIA3 Monoclonal Antibody (OTI4D7), TrueMAB™
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Product Details
TA505008S
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
OTI4D7
Immunogen
Human recombinant protein fragment corresponding to amino acids 140-505 of human PDIA3 produced in E.coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
30 µg
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 58 kDa glucose-regulated protein; 58 kDa microsomal protein; Disulfide isomerase ER-60; endoplasmic reticulum P58; Endoplasmic reticulum resident protein 57; Endoplasmic reticulum resident protein 60; epididymis secretory protein Li 269; epididymis secretory sperm binding protein Li 93n; ER p57; ER protein 57; ER protein 60; ERp 57; glucose regulated protein, 58kDa; GRP 57; GRP 58; p58; PDIA 3; phospholipase C-alpha; PI PLC; protein disulfide isomerase-associated 3; Protein disulfide-isomerase A3; unnamed protein product
Gene Aliases: ER60; ERP57; ERP60; ERp61; GRP57; GRP58; HEL-S-269; HEL-S-93n; HsT17083; P58; PDIA3; PI-PLC
UniProt ID: (Human) P30101
Entrez Gene ID: (Human) 2923
adaptive immune response
immune system process
peptide antigen assembly with MHC class I protein complex
protein folding
protein folding in endoplasmic reticulum
response to endoplasmic reticulum stress
platelet aggregation
extrinsic apoptotic signaling pathway
cellular response to interleukin-7
positive regulation of extrinsic apoptotic signaling pathway
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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