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OriGene
SFRP2 Monoclonal Antibody (OTI6C2), TrueMAB™
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Product Details
TA807497
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
OTI6C2
Immunogen
Human recombinant protein fragment corresponding to amino acids 25-295 of human SFRP2 produced in E.coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FRP 2; FRP-2; MGC128911; MGC153618; MGC53344; SARP 1; SARP-1; SDF 5; secreted apoptosis related protein 1; Secreted apoptosis-related protein 1; Secreted frizzled-related protein 2; sFRP 2; sFRP-2; Sfrp2 protein; similar to frizzled-like receptor CRD; testicular tissue protein Li 170; unnamed protein product
Gene Aliases: FKSG12; FRP-2; FRP2; SARP1; SDF-5; SFRP2; UNQ361/PRO697
UniProt ID: (Human) Q96HF1
Entrez Gene ID: (Human) 6423
regulation of cell growth
patterning of blood vessels
somitogenesis
neural tube closure
chondrocyte development
outflow tract morphogenesis
cardiac left ventricle morphogenesis
apoptotic process
cell-cell signaling
mesodermal cell fate specification
response to nutrient
positive regulation of cell proliferation
negative regulation of cell proliferation
male gonad development
response to xenobiotic stimulus
anterior/posterior pattern specification
negative regulation of gene expression
cardiac muscle cell apoptotic process
negative regulation of cardiac muscle cell apoptotic process
negative regulation of epithelial to mesenchymal transition
regulation of neuron projection development
Wnt signaling pathway
neural tube development
regulation of Wnt signaling pathway
cell differentiation
negative regulation of Wnt signaling pathway
collagen fibril organization
positive regulation of cell growth
negative regulation of cell growth
negative regulation of cell migration
BMP signaling pathway
negative regulation of BMP signaling pathway
positive regulation of cell adhesion mediated by integrin
non-canonical Wnt signaling pathway
post-anal tail morphogenesis
regulation of cell proliferation
negative regulation of mesodermal cell fate specification
embryonic digit morphogenesis
regulation of apoptotic process
positive regulation of apoptotic process
positive regulation of fat cell differentiation
positive regulation of osteoblast differentiation
positive regulation of angiogenesis
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
development of primary male sexual characteristics
digestive tract morphogenesis
stem cell fate specification
negative regulation of epithelial cell proliferation
negative regulation of peptidyl-tyrosine phosphorylation
cartilage development
convergent extension involved in axis elongation
canonical Wnt signaling pathway
sclerotome development
negative regulation of dermatome development
hematopoietic stem cell proliferation
cellular response to X-ray
negative regulation of canonical Wnt signaling pathway
regulation of establishment of planar polarity
Wnt signaling pathway involved in somitogenesis
positive regulation of canonical Wnt signaling pathway
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
regulation of midbrain dopaminergic neuron differentiation
regulation of stem cell division
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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