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Invitrogen
Human CASK (aa 578-592) Synthetic Peptide
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Product Details
PEP-110
Product Specifications
Class
Synthetic
Type
Peptide
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Amount
50 µg
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
PEP-110 is a 15 amino acid synthetic peptide whose sequence corresponds to amino acid residues 578-592 of human CASK. The sequence of this peptide is (amino to carboxy terminus): C (578)-E-R-D-S-P-S-T-S-R-Q-S-P-A-N (592)
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and human CASK, catalog # PA1-544. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.
Reconstitute with 0.1 mL of distilled water.
Target Information
CASK is a calcium/calmodulin-dependent serine protein kinase which is a MAGUK (membrane-associated guanylate kinase) protein family member. CASK is a scaffold protein and the encoded protein is located at synapses in the brain. CASK associates with FG syndrome 4, mental retardation, microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked mental retardation. CASK functions as a cytoskeletal membrane scaffold that coordinates signal transduction pathways within the cortical cytoskeleton.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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