SPB (succinimidyl-[4-(psoralen-8-yloxy)]-butyrate)

Thermo Scientific Pierce SPB is an NHS-ester and psoralen crosslinker that effectively conjugates primary amines to DNA via light-activated intercalation next to pyrimidine bases.

Features of SPB:

• Reactive groups: NHS ester and psoralen
• Reactive toward: amino groups and thymine
• DNA intercalating agent and nucleic acid probe^1,2
• Reagent for photo-immobilization to microplates³
• Melting point: 177-178°C

Product References:
Crosslinker Application Guide -- search for recent literature references for this product