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Invitrogen
IL1RL2 (Spesolimab Biosimilar) Recombinant Human Monoclonal Antibody
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Product Details
MA5-58648
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Human
/ IgG1
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Amount
1 mg
Purification
Protein A
Storage buffer
25mM histidine, pH 6.2, with 0.01% Tween 80, 8% sucrose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Product Specific Information
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.
Target Information
The protein encoded by this gene is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. This gene and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: IL-1 receptor-related protein 2; IL-1Rrp2; IL-36 receptor; IL-36R; Interleukin-1 receptor-like 2; Interleukin-1 receptor-related protein 2; unnamed protein product
Gene Aliases: IL-1Rrp2; IL-36R; IL1R-rp2; IL1RL2; IL1RRP2
UniProt ID: (Human) Q9HB29
Entrez Gene ID: (Human) 8808
immune system process
inflammatory response
cellular defense response
signal transduction
cell surface receptor signaling pathway
cytokine-mediated signaling pathway
positive regulation of interleukin-6 production
innate immune response
positive regulation of T cell differentiation
regulation of inflammatory response
interleukin-1-mediated signaling pathway
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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